Analysis of cellular signal transduction from an information theoretic approach

Shinsuke Uda, Shinya Kuroda

研究成果: ジャーナルへの寄稿評論記事

12 引用 (Scopus)

抄録

Signal transduction processes the information of various cellular functions, including cell proliferation, differentiation, and death. The information for controlling cell fate is transmitted by concentrations of cellular signaling molecules. However, how much information is transmitted in signaling pathways has thus far not been investigated. Shannon's information theory paves the way to quantitatively analyze information transmission in signaling pathways. The theory has recently been applied to signal transduction, and mutual information of signal transduction has been determined to be a measure of information transmission. We review this work and provide an overview of how signal transduction transmits informational input and exerts biological output.

元の言語英語
ページ(範囲)24-31
ページ数8
ジャーナルSeminars in Cell and Developmental Biology
51
DOI
出版物ステータス出版済み - 3 1 2016

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Signal Transduction
Information Theory
Cell Differentiation
Cell Death
Cell Proliferation

All Science Journal Classification (ASJC) codes

  • Developmental Biology
  • Cell Biology

これを引用

Analysis of cellular signal transduction from an information theoretic approach. / Uda, Shinsuke; Kuroda, Shinya.

:: Seminars in Cell and Developmental Biology, 巻 51, 01.03.2016, p. 24-31.

研究成果: ジャーナルへの寄稿評論記事

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