Analysis of cellular signal transduction from an information theoretic approach

Shinsuke Uda, Shinya Kuroda

研究成果: Contribution to journalReview article査読

19 被引用数 (Scopus)

抄録

Signal transduction processes the information of various cellular functions, including cell proliferation, differentiation, and death. The information for controlling cell fate is transmitted by concentrations of cellular signaling molecules. However, how much information is transmitted in signaling pathways has thus far not been investigated. Shannon's information theory paves the way to quantitatively analyze information transmission in signaling pathways. The theory has recently been applied to signal transduction, and mutual information of signal transduction has been determined to be a measure of information transmission. We review this work and provide an overview of how signal transduction transmits informational input and exerts biological output.

本文言語英語
ページ(範囲)24-31
ページ数8
ジャーナルSeminars in Cell and Developmental Biology
51
DOI
出版ステータス出版済み - 3 1 2016

All Science Journal Classification (ASJC) codes

  • 発生生物学
  • 細胞生物学

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