Analysis of Stereochemical Stability of Dynamic Chiral Molecules Using an Automated Microflow Measurement System

研究成果: Contribution to journalArticle査読

抄録

An automated microflow measurement system for the kinetic study of racemization of dynamic chiral molecules was developed. This system facilitated the analysis of fast racemization within several seconds at elevated temperatures owing to its rapid heating ability, high performance for controlling short residence times, and ease of connection to HPLC systems for direct measurement of the enantiomeric purity. A more precise analysis was realized by combination of microflow and common batch measurements over a broad range of temperatures.

本文言語英語
ページ(範囲)9651-9657
ページ数7
ジャーナルJournal of Organic Chemistry
86
14
DOI
出版ステータス出版済み - 7 16 2021

All Science Journal Classification (ASJC) codes

  • 有機化学

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