Angiogenesis as a new target for cancer treatment

Mayumi Ono, Hiroto Izumi, Shigeo Yoshida, Daisuke Goto, Sei Ichiro Jimi, Naoyuki Kawahara, Tadahisa Shono, Shin Ushiro, Masahiro Ryuto, Kimitoshi Kohno, Yasafumi Sato, Michihiko Kuwano

研究成果: Contribution to journalArticle査読

6 被引用数 (Scopus)


Neovascularization is often required for rapid growth of solid tumors and also limits vascular metastasis of tumor cells. Neovascularization-targeting agents are a recent innovation that may be a novel means of anticancer therapy. These antiangiogenic drugs have been developed by targeting cell proliferation of vascular endothelial cells, basement-membrane-degrading enzymes, angiogenic factors/receptors, extracellular matrix, angiogenesis signaling, and cell-cell/cell-matrix interactions. In this report, we describe how tumor angiogenesis occurs and how antiangiogenic agents are developed.

ジャーナルCancer Chemotherapy and Pharmacology, Supplement
出版ステータス出版済み - 1996

All Science Journal Classification (ASJC) codes

  • Oncology
  • Pharmacology
  • Cancer Research

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