Anti-allergic activity of lotus root (Nelumbo nucifera) powder in TDI-sensitized nasal allergy model mice

Mayumi Kaneyasu, Maki Nagata, Hiromi Ikeda, Koichiro Ohnuki, Kuniyoshi Shimizu

研究成果: Contribution to journalArticle査読

3 被引用数 (Scopus)

抄録

Lotus root (Nelumbo nucifera) is a popular food in Japan and southeast Asia. It is reported that lotus root includes dietary fiber, vitamin C, and abundant polyphenolic compounds. In Chinese medicine, lotus powder is also utilized in anti-tussive or anti-inflammatory drugs. In this study, we focused on the effects of lotus root powder on allergy symptoms in mice. First, we assessed nasal allergy symptoms in 2,4-diisocyanic acid toluene (TDI)-sensitized nasal allergy model mice. We found that lotus root powder alleviated nasal allergy symptoms in the mice. In addition, we estimated serum inflammatory parameters such as serum total IgE, histamine, and leukotriene B4. Lotus root powder intake significantly decreased serum total IgE and leukotriene B4 compared with standard food intake. We suggest that lotus root powder intake may alleviate allergic symptoms.

本文言語英語
ページ(範囲)968-978
ページ数11
ジャーナルFood and Agricultural Immunology
30
1
DOI
出版ステータス出版済み - 2019

All Science Journal Classification (ASJC) codes

  • Food Science
  • Immunology
  • Agronomy and Crop Science

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