Anti-androgenic activities of Ganoderma lucidum

Rumi Fujita; Jie Liu; Kuniyoshi Shimizu; Fumiko Konishi; Kiyoshi Noda; Shoichiro Kumamoto; Chie Ueda; Hisatoshi Tajiri; Shuhei Kaneko; Yoshitaro Suimi; Ryuichiro Kondo

doi:10.1016/j.jep.2005.05.041

Anti-androgenic activities of Ganoderma lucidum

Rumi Fujita, Jie Liu, Kuniyoshi Shimizu, Fumiko Konishi, Kiyoshi Noda, Shoichiro Kumamoto, Chie Ueda, Hisatoshi Tajiri, Shuhei Kaneko, Yoshitaro Suimi, Ryuichiro Kondo

サスティナブル資源科学

研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

51 被引用数 (Scopus)

抄録

The inhibitory effects of methanol extracts of 19 edible and medicinal mushrooms on 5α-reductase activity were examined. The extract of Ganoderma lucidum Fr. Krast (Ganodermataceae) showed the strongest 5α-reductase inhibitory activity. The treatment of the fruit body of Ganoderma lucidum or the extract prepared from it significantly inhibited the testosterone-induced growth of the ventral prostate in castrated rats. These results showed that Ganoderma lucidum might be a useful ingredient for the treatment of benign prostatic hyperplasia (BPH).

本文言語	英語
ページ（範囲）	107-112
ページ数	6
ジャーナル	Journal of Ethnopharmacology
巻	102
号	1
DOI	https://doi.org/10.1016/j.jep.2005.05.041
出版ステータス	出版済み - 10月 31 2005

!!!All Science Journal Classification (ASJC) codes

薬理学
創薬

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10.1016/j.jep.2005.05.041

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title = "Anti-androgenic activities of Ganoderma lucidum",

abstract = "The inhibitory effects of methanol extracts of 19 edible and medicinal mushrooms on 5α-reductase activity were examined. The extract of Ganoderma lucidum Fr. Krast (Ganodermataceae) showed the strongest 5α-reductase inhibitory activity. The treatment of the fruit body of Ganoderma lucidum or the extract prepared from it significantly inhibited the testosterone-induced growth of the ventral prostate in castrated rats. These results showed that Ganoderma lucidum might be a useful ingredient for the treatment of benign prostatic hyperplasia (BPH).",

author = "Rumi Fujita and Jie Liu and Kuniyoshi Shimizu and Fumiko Konishi and Kiyoshi Noda and Shoichiro Kumamoto and Chie Ueda and Hisatoshi Tajiri and Shuhei Kaneko and Yoshitaro Suimi and Ryuichiro Kondo",

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doi = "10.1016/j.jep.2005.05.041",

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TY - JOUR

T1 - Anti-androgenic activities of Ganoderma lucidum

AU - Fujita, Rumi

AU - Liu, Jie

AU - Shimizu, Kuniyoshi

AU - Konishi, Fumiko

AU - Noda, Kiyoshi

AU - Kumamoto, Shoichiro

AU - Ueda, Chie

AU - Tajiri, Hisatoshi

AU - Kaneko, Shuhei

AU - Suimi, Yoshitaro

AU - Kondo, Ryuichiro

PY - 2005/10/31

Y1 - 2005/10/31

N2 - The inhibitory effects of methanol extracts of 19 edible and medicinal mushrooms on 5α-reductase activity were examined. The extract of Ganoderma lucidum Fr. Krast (Ganodermataceae) showed the strongest 5α-reductase inhibitory activity. The treatment of the fruit body of Ganoderma lucidum or the extract prepared from it significantly inhibited the testosterone-induced growth of the ventral prostate in castrated rats. These results showed that Ganoderma lucidum might be a useful ingredient for the treatment of benign prostatic hyperplasia (BPH).

AB - The inhibitory effects of methanol extracts of 19 edible and medicinal mushrooms on 5α-reductase activity were examined. The extract of Ganoderma lucidum Fr. Krast (Ganodermataceae) showed the strongest 5α-reductase inhibitory activity. The treatment of the fruit body of Ganoderma lucidum or the extract prepared from it significantly inhibited the testosterone-induced growth of the ventral prostate in castrated rats. These results showed that Ganoderma lucidum might be a useful ingredient for the treatment of benign prostatic hyperplasia (BPH).

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JO - Journal of Ethnopharmacology

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Anti-androgenic activities of Ganoderma lucidum

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!!!All Science Journal Classification (ASJC) codes

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