Anti-androgenic activities of Ganoderma lucidum

Rumi Fujita, Jie Liu, Kuniyoshi Shimizu, Fumiko Konishi, Kiyoshi Noda, Shoichiro Kumamoto, Chie Ueda, Hisatoshi Tajiri, Shuhei Kaneko, Yoshitaro Suimi, Ryuichiro Kondo

研究成果: ジャーナルへの寄稿記事

61 引用 (Scopus)

抜粋

The inhibitory effects of methanol extracts of 19 edible and medicinal mushrooms on 5α-reductase activity were examined. The extract of Ganoderma lucidum Fr. Krast (Ganodermataceae) showed the strongest 5α-reductase inhibitory activity. The treatment of the fruit body of Ganoderma lucidum or the extract prepared from it significantly inhibited the testosterone-induced growth of the ventral prostate in castrated rats. These results showed that Ganoderma lucidum might be a useful ingredient for the treatment of benign prostatic hyperplasia (BPH).

元の言語英語
ページ(範囲)107-112
ページ数6
ジャーナルJournal of Ethnopharmacology
102
発行部数1
DOI
出版物ステータス出版済み - 10 31 2005

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery

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    Fujita, R., Liu, J., Shimizu, K., Konishi, F., Noda, K., Kumamoto, S., Ueda, C., Tajiri, H., Kaneko, S., Suimi, Y., & Kondo, R. (2005). Anti-androgenic activities of Ganoderma lucidum. Journal of Ethnopharmacology, 102(1), 107-112. https://doi.org/10.1016/j.jep.2005.05.041