Anti-biofouling properties of polymers with a carboxybetaine moiety

Sulumu Tada, Chika Inaba, Kazuya Mizukami, Shigeto Fujishita, Makoto Geminei-Ide, Hiromi Kitano, Akira Mochizuki, Masaru Tanaka, Takayuki Matsunaga

研究成果: Contribution to journalArticle査読

75 被引用数 (Scopus)

抄録

The resistance of random copolymers of BMA and CMB against biofouling was evaluated. The amount of proteins adsorbed onto the CMB copolymers was smaller than that onto other polymers (non-ionic polymers and copolymers of ordinary ionic monomers and BMA) and decreased with an increase in the content of CMB residues. Furthermore, there was a dramatic decrease in the number of cells (platelets and fibroblasts) that adhered to the CMB copolymers compared with that to other polymers. In contrast with this, CMB copolymers were slightly perturbative to both complement and coagulation systems. However, the overall results suggest that zwitterionic moieties are effective for making polymer materials biocompatible due to their excellent anti-biofouling property. A graph is presented.

本文言語英語
ページ(範囲)63-70
ページ数8
ジャーナルMacromolecular Bioscience
9
1
DOI
出版ステータス出版済み - 1 9 2009
外部発表はい

All Science Journal Classification (ASJC) codes

  • バイオテクノロジー
  • バイオエンジニアリング
  • 生体材料
  • ポリマーおよびプラスチック
  • 材料化学

フィンガープリント

「Anti-biofouling properties of polymers with a carboxybetaine moiety」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル