The aim of this study was to evaluate the anti-diabetic potential of acetic acid-free red vinegar (RV) containing a candidate, 6-O-caffeoylsophorose (CS), in spontaneously diabetic Torii (SDT) rats. In accordance with administration protocols, ingestion by SDT began between the ages of 11 and 16 weeks which corresponded to normal and prediabetic stages, respectively. Daily intake of RV (4.3 mg/kg/day) led to a significant reduction in fasting blood glucose level (BGL) in 28-wk SDT (fasting BGL: control, 133.8±12.8 mg/mL; RV, 98.5±19.8 mg/mL), while no anti-diabetic effect was obtained in SDT fed from 27 weeks of age. These results demonstrated that RV has physiological potential to suppress promotion of diabetes, but not to improve the developed of onset.
All Science Journal Classification (ASJC) codes
- Food Science