Anti-dorsal root ganglion neuron antibody in a case of dorsal root ganglionitis associated with Sjögren's syndrome

Marie Satake, Takeo Yoshimura, Toru Iwaki, Takeshi Yamada, Takuro Kobayashi

研究成果: Contribution to journalArticle査読

25 被引用数 (Scopus)

抄録

We report the case of a 59-year-old woman with primary Sjögren's syndrome who developed hypesthesia, hypalgesia, and neurogenic arthropathy in her lower limbs. Neurological examination and electrophysiological studies indicated involvement of the dorsal root ganglia. The immunohistochemistry of sections of rat dorsal root ganglion (DRG) showed that the IgG in the serum and cerebrospinal fluid (CSF) from the patient bound to the neuronal perikarya of small DRG neurons but not to the cerebellum or peripheral nerves. These results, consistent with particular impairment of pain and touch senses, suggest that dorsal root ganglionitis in primary Sjögren's syndrome is mediated by humoral autoimmunity.

本文言語英語
ページ(範囲)122-125
ページ数4
ジャーナルJournal of the Neurological Sciences
132
2
DOI
出版ステータス出版済み - 10 1995
外部発表はい

All Science Journal Classification (ASJC) codes

  • 神経学
  • 臨床神経学

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