Antibacterial activity of Nepalese wild mushrooms against Staphylococcus aureus and Propionibacterium acnes

Sonam Tamrakar, Marina Nishida, Yhiya Amen, Hai Bang Tran, Hiroto Suhara, Katsuya Fukami, Gopal Prasad Parajuli, Kuniyoshi Shimizu

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

抄録

The present study aims to reveal the antibacterial potential of the wild mushrooms of Nepal. Despite the recognition of the medicinal potential of the natural resources in this country, a systematic study on the bioactivities of the wild mushrooms is still lacking. Therefore, in an attempt to fill this gap, ethanol extracts of 90 Nepalese wild mushroom samples were tested for antibacterial activity against Staphylococcus aureus and Propionibacterium acnes. Staphylococcus aureus was comparatively more susceptible with Inonotus clemensiae exhibiting the least minimum bactericidal concentration (MBC) of 100 μg/mL. The major compound in I. clemensiae was identified to be hispidin using high resolution liquid chromatography–electron spray ionization mass spectrometry (LC–ESI-MS) and nuclear magnetic resonance (NMR) analyses. Furthermore, the minimum inhibitory concentration (MIC) and MBC values of hispidin were determined to be 25 and 100 µg/mL for S. aureus and P. acnes, respectively. These findings show that the Nepalese wild mushrooms have the potential to be a novel addition to the functional ingredients industry due to their strong antibacterial potential.

元の言語英語
ページ(範囲)379-387
ページ数9
ジャーナルJournal of Wood Science
63
発行部数4
DOI
出版物ステータス出版済み - 8 1 2017

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Natural resources
Bioactivity
Ionization
Mass spectrometry
Ethanol
Nuclear magnetic resonance
Liquids
Industry
hispidin

All Science Journal Classification (ASJC) codes

  • Biomaterials

これを引用

Antibacterial activity of Nepalese wild mushrooms against Staphylococcus aureus and Propionibacterium acnes. / Tamrakar, Sonam; Nishida, Marina; Amen, Yhiya; Tran, Hai Bang; Suhara, Hiroto; Fukami, Katsuya; Parajuli, Gopal Prasad; Shimizu, Kuniyoshi.

:: Journal of Wood Science, 巻 63, 番号 4, 01.08.2017, p. 379-387.

研究成果: ジャーナルへの寄稿記事

Tamrakar, Sonam ; Nishida, Marina ; Amen, Yhiya ; Tran, Hai Bang ; Suhara, Hiroto ; Fukami, Katsuya ; Parajuli, Gopal Prasad ; Shimizu, Kuniyoshi. / Antibacterial activity of Nepalese wild mushrooms against Staphylococcus aureus and Propionibacterium acnes. :: Journal of Wood Science. 2017 ; 巻 63, 番号 4. pp. 379-387.
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abstract = "The present study aims to reveal the antibacterial potential of the wild mushrooms of Nepal. Despite the recognition of the medicinal potential of the natural resources in this country, a systematic study on the bioactivities of the wild mushrooms is still lacking. Therefore, in an attempt to fill this gap, ethanol extracts of 90 Nepalese wild mushroom samples were tested for antibacterial activity against Staphylococcus aureus and Propionibacterium acnes. Staphylococcus aureus was comparatively more susceptible with Inonotus clemensiae exhibiting the least minimum bactericidal concentration (MBC) of 100 μg/mL. The major compound in I. clemensiae was identified to be hispidin using high resolution liquid chromatography–electron spray ionization mass spectrometry (LC–ESI-MS) and nuclear magnetic resonance (NMR) analyses. Furthermore, the minimum inhibitory concentration (MIC) and MBC values of hispidin were determined to be 25 and 100 µg/mL for S. aureus and P. acnes, respectively. These findings show that the Nepalese wild mushrooms have the potential to be a novel addition to the functional ingredients industry due to their strong antibacterial potential.",
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AU - Suhara, Hiroto

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AU - Parajuli, Gopal Prasad

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