Antibody internalization into living cells via crosslinker-mediated endocytosis

Daiki Funamoto, Daisuke Asai, Kazuki Sato, Yoko Yamaguchi, Chan Woo Kim, Hikari Sato, Elnaz Nakhaei, Shingo Matsumoto, Takuma Yoshikawa, Koichi Sasaki, Tatsuhiro Yamamoto, Akihiro Kishimura, Takeshi Mori, Yoshiki Katayama

研究成果: ジャーナルへの寄稿記事

抄録

We reported here an alternative strategy of antibody internalization by crosslinker-mediated endocytosis. This cross-linker consists of IgG binding peptide and folic acid as cancer targeting ligands toward the folate receptor, which highly expresses in many cancer cells surface. This crosslinker successfully facilitated antibody internalization into cancer cell by the folate receptor-mediated endocytosis.

元の言語英語
ページ(範囲)468-470
ページ数3
ジャーナルChemistry Letters
44
発行部数4
DOI
出版物ステータス出版済み - 1 1 2015

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Folic Acid
Cells
Antibodies
Immunoglobulin G
Ligands
Peptides

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

これを引用

Funamoto, D., Asai, D., Sato, K., Yamaguchi, Y., Kim, C. W., Sato, H., ... Katayama, Y. (2015). Antibody internalization into living cells via crosslinker-mediated endocytosis. Chemistry Letters, 44(4), 468-470. https://doi.org/10.1246/cl.141157

Antibody internalization into living cells via crosslinker-mediated endocytosis. / Funamoto, Daiki; Asai, Daisuke; Sato, Kazuki; Yamaguchi, Yoko; Kim, Chan Woo; Sato, Hikari; Nakhaei, Elnaz; Matsumoto, Shingo; Yoshikawa, Takuma; Sasaki, Koichi; Yamamoto, Tatsuhiro; Kishimura, Akihiro; Mori, Takeshi; Katayama, Yoshiki.

:: Chemistry Letters, 巻 44, 番号 4, 01.01.2015, p. 468-470.

研究成果: ジャーナルへの寄稿記事

Funamoto, D, Asai, D, Sato, K, Yamaguchi, Y, Kim, CW, Sato, H, Nakhaei, E, Matsumoto, S, Yoshikawa, T, Sasaki, K, Yamamoto, T, Kishimura, A, Mori, T & Katayama, Y 2015, 'Antibody internalization into living cells via crosslinker-mediated endocytosis', Chemistry Letters, 巻. 44, 番号 4, pp. 468-470. https://doi.org/10.1246/cl.141157
Funamoto D, Asai D, Sato K, Yamaguchi Y, Kim CW, Sato H その他. Antibody internalization into living cells via crosslinker-mediated endocytosis. Chemistry Letters. 2015 1 1;44(4):468-470. https://doi.org/10.1246/cl.141157
Funamoto, Daiki ; Asai, Daisuke ; Sato, Kazuki ; Yamaguchi, Yoko ; Kim, Chan Woo ; Sato, Hikari ; Nakhaei, Elnaz ; Matsumoto, Shingo ; Yoshikawa, Takuma ; Sasaki, Koichi ; Yamamoto, Tatsuhiro ; Kishimura, Akihiro ; Mori, Takeshi ; Katayama, Yoshiki. / Antibody internalization into living cells via crosslinker-mediated endocytosis. :: Chemistry Letters. 2015 ; 巻 44, 番号 4. pp. 468-470.
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