Antibody internalization into living cells via crosslinker-mediated endocytosis

Daiki Funamoto, Daisuke Asai, Kazuki Sato, Yoko Yamaguchi, Chan Woo Kim, Hikari Sato, Elnaz Nakhaei, Shingo Matsumoto, Takuma Yoshikawa, Koichi Sasaki, Tatsuhiro Yamamoto, Akihiro Kishimura, Takeshi Mori, Yoshiki Katayama

研究成果: Contribution to journalArticle査読

抄録

We reported here an alternative strategy of antibody internalization by crosslinker-mediated endocytosis. This cross-linker consists of IgG binding peptide and folic acid as cancer targeting ligands toward the folate receptor, which highly expresses in many cancer cells surface. This crosslinker successfully facilitated antibody internalization into cancer cell by the folate receptor-mediated endocytosis.

本文言語英語
ページ(範囲)468-470
ページ数3
ジャーナルChemistry Letters
44
4
DOI
出版ステータス出版済み - 2015

All Science Journal Classification (ASJC) codes

  • 化学 (全般)

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