ANTIOXIDANT AND ANTI-LIPASE COMPOUNDS ISOLATED FROM HEARTWOOD OF YAKUSHIMA NATIVE CEDAR (Cryptomeria japonica)

Toshinori Nakagawa, Ahmed Ashour, Yhiya Amen, Koichiro Ohnuki, Noboru Fujimoto, Kuniyoshi Shimizu

研究成果: ジャーナルへの寄稿記事

抄録

This article describes the biological activities of heartwood extracts from Yakushima native cedar (Cryptomeria japonica) and identifies their main active compounds. Black heartwood and red heartwood were each divided into two parts from the center (the pith) to outer heartwood (the cambium). The methanol extracts of those parts were screened for antioxidant and anti-lipase activities. The extract from the pith of the red heartwood showed the highest ORAC activity among the samples. Regarding anti-lipase activity, all the extracts showed relatively high activity (the IC50 value were 9.71–37.24 μg mL−1). In addition, four compounds were isolated and identified from the pith of red heartwood by NMR and MS analyses. Agatharesinol (3) and sequirin C (4) were thought to be the main active compounds responsible for the antioxidant and anti-lipase activities.

元の言語英語
ページ(範囲)305-312
ページ数8
ジャーナルJournal of Wood Chemistry and Technology
39
発行部数5
DOI
出版物ステータス出版済み - 9 3 2019

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Lipases
Antioxidants
Lipase
Bioactivity
Methanol
Nuclear magnetic resonance

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)
  • Materials Science(all)

これを引用

ANTIOXIDANT AND ANTI-LIPASE COMPOUNDS ISOLATED FROM HEARTWOOD OF YAKUSHIMA NATIVE CEDAR (Cryptomeria japonica). / Nakagawa, Toshinori; Ashour, Ahmed; Amen, Yhiya; Ohnuki, Koichiro; Fujimoto, Noboru; Shimizu, Kuniyoshi.

:: Journal of Wood Chemistry and Technology, 巻 39, 番号 5, 03.09.2019, p. 305-312.

研究成果: ジャーナルへの寄稿記事

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abstract = "This article describes the biological activities of heartwood extracts from Yakushima native cedar (Cryptomeria japonica) and identifies their main active compounds. Black heartwood and red heartwood were each divided into two parts from the center (the pith) to outer heartwood (the cambium). The methanol extracts of those parts were screened for antioxidant and anti-lipase activities. The extract from the pith of the red heartwood showed the highest ORAC activity among the samples. Regarding anti-lipase activity, all the extracts showed relatively high activity (the IC50 value were 9.71–37.24 μg mL−1). In addition, four compounds were isolated and identified from the pith of red heartwood by NMR and MS analyses. Agatharesinol (3) and sequirin C (4) were thought to be the main active compounds responsible for the antioxidant and anti-lipase activities.",
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