TY - JOUR
T1 - Antioxidative compounds from leaves of Tahongai (Klienhovia hospita)
AU - Arung, Enos Tangke
AU - Kusuma, Irawan Wijaya
AU - Kim, Yong Ung
AU - Shimizu, Kuniyoshi
AU - Kondo, Ryuichiro
N1 - Funding Information:
Acknowledgments This work was funded by DIKTI of Indonesian Education Ministry with Grant No. 026/SP2H/PP/DP2M/III/2008.
PY - 2012/2
Y1 - 2012/2
N2 - In our effort to find antioxidant agent, we focused on Tahongai (Kleinhovia hospita) which have been used traditionally in Indonesia as medicinal herbal to cure liver disease. Based on the biologically guided fractionation using DPPH radical scavenging assay, eleutherol and kaempferol 3-O-β-D-glucoside was isolated from the leaves of K. hospita. Kaempferol 3-O-β-D-glucoside (1) and eleutherol (2) scavenged the radical with IC 50 of 71. 4 and 491. 8 μM, respectively. In addition, both of the compounds did not exhibit cytotoxicity on HepG2 cells.
AB - In our effort to find antioxidant agent, we focused on Tahongai (Kleinhovia hospita) which have been used traditionally in Indonesia as medicinal herbal to cure liver disease. Based on the biologically guided fractionation using DPPH radical scavenging assay, eleutherol and kaempferol 3-O-β-D-glucoside was isolated from the leaves of K. hospita. Kaempferol 3-O-β-D-glucoside (1) and eleutherol (2) scavenged the radical with IC 50 of 71. 4 and 491. 8 μM, respectively. In addition, both of the compounds did not exhibit cytotoxicity on HepG2 cells.
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U2 - 10.1007/s10086-011-1217-7
DO - 10.1007/s10086-011-1217-7
M3 - Article
AN - SCOPUS:84857367162
SN - 1435-0211
VL - 58
SP - 77
EP - 80
JO - Journal of Wood Science
JF - Journal of Wood Science
IS - 1
ER -