Antiphospholipid syndrome complicated by unilateral pleural effusion

Yasutaka Mitamura, Masakazu Takahara, Takamichi Ito, Misa Nakano, Yoichi Moroi, Masutaka Furue

研究成果: ジャーナルへの寄稿記事

抄録

Antiphospholipid syndrome (APS) with pleural effusion is extremely rare. A 75-year-old man was admitted to our hospital for spreading erythema on his trunk and extremities, as well as dyspnea. One year before admission, he had visited us with a 1-year history of erythema and purpura on his legs and occasional fever. Given the diagnosis of APS, we initiated a combination therapy of aspirin and warfarin, but the skin lesions had gradually worsened. A biopsy specimen revealed marked thrombosis in the dermal and subcutaneous small vessels. In addition, chest X-ray and computed tomography demonstrated a large pleural effusion in the left lung. He underwent repeated drainage of the pleural effusion but the effusion recurred. We added oral prednisolone 30 mg daily to his prior anticoagulant therapy. The skin lesions and pleural effusion rapidly improved and disappeared without any complication. Corticosteroids might be a choice of treatment for intractable pleural effusion in APS patients.

元の言語英語
ページ(範囲)198-202
ページ数5
ジャーナルCase Reports in Dermatology
5
発行部数2
DOI
出版物ステータス出版済み - 5 1 2013

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Antiphospholipid Syndrome
Pleural Effusion
Erythema
Skin
Purpura
X Ray Computed Tomography
Warfarin
Prednisolone
Dyspnea
Anticoagulants
Aspirin
Drainage
Leg
Adrenal Cortex Hormones
Thrombosis
Fever
Thorax
Therapeutics
Extremities
Biopsy

All Science Journal Classification (ASJC) codes

  • Dermatology

これを引用

Antiphospholipid syndrome complicated by unilateral pleural effusion. / Mitamura, Yasutaka; Takahara, Masakazu; Ito, Takamichi; Nakano, Misa; Moroi, Yoichi; Furue, Masutaka.

:: Case Reports in Dermatology, 巻 5, 番号 2, 01.05.2013, p. 198-202.

研究成果: ジャーナルへの寄稿記事

Mitamura, Yasutaka ; Takahara, Masakazu ; Ito, Takamichi ; Nakano, Misa ; Moroi, Yoichi ; Furue, Masutaka. / Antiphospholipid syndrome complicated by unilateral pleural effusion. :: Case Reports in Dermatology. 2013 ; 巻 5, 番号 2. pp. 198-202.
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AU - Moroi, Yoichi

AU - Furue, Masutaka

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N2 - Antiphospholipid syndrome (APS) with pleural effusion is extremely rare. A 75-year-old man was admitted to our hospital for spreading erythema on his trunk and extremities, as well as dyspnea. One year before admission, he had visited us with a 1-year history of erythema and purpura on his legs and occasional fever. Given the diagnosis of APS, we initiated a combination therapy of aspirin and warfarin, but the skin lesions had gradually worsened. A biopsy specimen revealed marked thrombosis in the dermal and subcutaneous small vessels. In addition, chest X-ray and computed tomography demonstrated a large pleural effusion in the left lung. He underwent repeated drainage of the pleural effusion but the effusion recurred. We added oral prednisolone 30 mg daily to his prior anticoagulant therapy. The skin lesions and pleural effusion rapidly improved and disappeared without any complication. Corticosteroids might be a choice of treatment for intractable pleural effusion in APS patients.

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