Anxa9 gene expression in colorectal cancer: A novel marker for prognosis

Norikatsu Miyoshi, Hirofumi Yamamoto, Koshi Mimori, Shinya Yamashita, Susumu Miyazaki, Sumiko Nakagawa, Hideshi Ishii, Shingo Noura, Masayuki Ohue, Masahiko Yano, Yuichiro Doki, Masaki Mori

研究成果: Contribution to journalArticle査読

10 被引用数 (Scopus)

抄録

Annexin A9 (ANXA9) is involved with the interaction with membrane phospholipids in a Ca2+-dependent manner. A previous study has shown that ANXA9 expression is associated with bone metastasis in breast cancer, whereas its significance in colorectal cancer (CRC) is unknown. The present study was comprised of 100 patients who underwent surgery for CRC. The correlation between gene expression and the clinical parameters of the patients was assessed. Patients with high ANXA9 expression were statistically susceptible to a relatively worse prognosis, and those with low ANXA9 expression showed improved overall survival compared with those with high expression. In conclusion, the present data suggests that ANXA9 expression is a prognostic factor in CRC patients.

本文言語英語
ページ(範囲)2313-2317
ページ数5
ジャーナルOncology Letters
8
5
DOI
出版ステータス出版済み - 11 1 2014
外部発表はい

All Science Journal Classification (ASJC) codes

  • 腫瘍学
  • 癌研究

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