Argon laser angioplasty with a laser probe

Yeng Yang, Makoto Hashizume, David Arbutina, Leonard F. Milewski, Joseph DuPree, Teruo Matsumoto

研究成果: Contribution to journalArticle査読

10 被引用数 (Scopus)


A preliminary basic study of argon laser angioplasty with the use of a specially designed probe is presented. Arterial specimens were harvested from 10 amputated lower extremities. The studies included (1) the evaluation of coaxial laser angioplasty in 10 partially or totally occluded arteries; (2) the observation of the effect of perpendicularly applied laser energy on 35 thrombi, 54 soft and 10 hard atherosclerotic, and 51 normal arterial walls; (3) the comparison of laser energy requirements for coaxial vessel lumen enlargement or recanalization vs. perpendicular penetration in 10 occluded, hard atherosclerotic arteries; and (4) the spectrographic analysis of calcium density gradient in two specimens. The results showed that the power required for vessel lumen enlargement was 10 ± 6 J/mm of atherosclerotic vessel (mean ± standard deviation). The probe followed the original arterial lumen, did not perforate the vessel wall, and created a smooth, enlarged path. The power required to penetrate perpendicularly to a similar depth for thrombi, soft and hard atherosclerotic plaques, and normal arterial walls was 15 ± 4, 30 ± 15, 65 ± 32, and 246 ± 123 J/mm, respectively. In the hard calcified specimens, laser energy required for coaxial lumen enlargement or recanalization was significantly less than that for perpendicular penetration (p <0.05), which correlated with the calcium density map indicating an increase from inside to outside. (J VASC SURG 1987;6:60-5.)

ジャーナルJournal of Vascular Surgery
出版ステータス出版済み - 1987

All Science Journal Classification (ASJC) codes

  • 外科
  • 循環器および心血管医学


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