Artificial baroreflex system restores volume tolerance in the absence of native baroreflex

Kazuya Hosokawa, Kouta Funakoshi, Atsushi Tanaka, Takafumi Sakamoto, Ken Onitsuka, Kazuo Sakamoto, Tomoyuki Tobushi, Takeo Fujino, Keita Saku, Yoshinori Murayama, Tomomi Ide, Kenji Sunagawa

研究成果: 書籍/レポート タイプへの寄稿会議への寄与

2 被引用数 (Scopus)

抄録

The arterial baroreflex stabilizes arterial pressure by modulating the mechanical properties of cardiovascular system. We previously demonstrated that the baroreflex impairment makes the circulatory system extremely sensitive to volume overload and predisposes to pulmonary edema irrespective of left ventricular systolic function. To overcome the volume intolerance, we developed an artificial baroreflex system by directly stimulating the carotid sinus nerves in response to changes in arterial pressure. The artificial baroreflex system precisely reproduced the native arterial pressure response and restored physiological volume buffering function. We conclude that the artificial baroreflex system would be an attractive tool in preventing pulmonary edema in patients with impaired baroreflex function.

本文言語英語
ホスト出版物のタイトル33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
ページ697-699
ページ数3
DOI
出版ステータス出版済み - 2011
イベント33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 - Boston, MA, 米国
継続期間: 8月 30 20119月 3 2011

出版物シリーズ

名前Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN(印刷版)1557-170X

その他

その他33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
国/地域米国
CityBoston, MA
Period8/30/119/3/11

!!!All Science Journal Classification (ASJC) codes

  • 信号処理
  • 生体医工学
  • コンピュータ ビジョンおよびパターン認識
  • 健康情報学

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