Artificial peptide-nanospheres self-assembled from three-way junctions of β-sheet-forming peptides

Kazunori Matsuura, Kazuya Murasato, Nobuo Kimizuka

    研究成果: Contribution to journalArticle査読

    119 被引用数 (Scopus)

    抄録

    Rational design of self-assembly of proteins, which plays pivotal roles in biology, is an important subject for biotechnology and also bottom-up nanotechnology. This paper has proposed a novel strategy for construction of artificial peptide-nanospheres by self-assembly. Mimicking formation of spherical viruses and clathrin, we designed a novel C3-symmetric peptide conjugate bearing three β-sheet-forming peptides. These peptide conjugates formed antiparallel β-structures and self-assembled into nanospheres with the size of about 20 nm in the acidic solution.

    本文言語英語
    ページ(範囲)10148-10149
    ページ数2
    ジャーナルJournal of the American Chemical Society
    127
    29
    DOI
    出版ステータス出版済み - 7 27 2005

    All Science Journal Classification (ASJC) codes

    • Catalysis
    • Chemistry(all)
    • Biochemistry
    • Colloid and Surface Chemistry

    フィンガープリント 「Artificial peptide-nanospheres self-assembled from three-way junctions of β-sheet-forming peptides」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

    引用スタイル