Assessing current nutritional status of patients with HCV-related liver cirrhosis in the compensated stage

Kenichiro Yasutake, Machiko Bekki, Masako Ichinose, Michiko Ikemoto, Tatsuya Fujino, Tomoki Ryu, Yoshiyuki Wada, Yuko Takami, Hideki Saitsu, Motoyuki Kohjima, Kunitaka Fukuizumi, Manabu Nakashima, Makoto Nakamuta, Munechika Enjoji

研究成果: Contribution to journalArticle査読

12 被引用数 (Scopus)


Background/Aim: Nutritional states of Japanese patients with liver cirrhosis have recently shown great diversity, some show protein energy malnutrition and others excessive nutrition and obesity. For there to be adequate guidance regarding dietary treatment, it is important that a patient's current nutritional state be clarified. Methods: We assessed nutritive intake in Japanese cirrhotic patients and determined their nutritional problems. Subjects were non-hospitalized patients with hepatitis C virus (HCV)-related cirrhosis in the compensated stage (n=47), chronic hepatitis C (n=46) or healthy volunteers (n=32). A brief self-administered diet history questionnaire was conducted with assistance from a registered dietitian. Results: We categorized patients with cirrhosis according to daily intake of energy and protein; 10.6% had an energy and protein intake within a normal range, 72.4% showed excessive intake, and 17.0% showed insufficient intake of energy or protein. In cirrhotic patients with diabetic complications, the intake levels of energy, proteins, fat and carbohydrates were significantly higher than in patients without diabetes. Moreover, cirrhotic patients had significantly higher intake levels of energy, protein and fat than did chronic hepatitis C patients and healthy individuals. In patients with HCV-related liver cirrhosis, nsufficient intake of energy and protein was shown in some, while many, especially tihose with diabetes, showed excessive intake. Conclusion: For nutritive management of cirrhotic patients, the intake of various nutrients should be appropriately assessed and effective nutritional education systems established.

ジャーナルAsia Pacific Journal of Clinical Nutrition
出版ステータス出版済み - 9 2012

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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