Assessment of delayed gastric emptying after major hepatectomy using a 13C-acetic acid breath test

Keishi Sugimachi, Ken Shirabe, Noriko Tokunaga, Hirotada Akiho, Akinobu Taketomi, Yuji Soejima, Tomonobu Gion, Kazuhiko Nakamura, Hidefumi Higashi, Yoshihiko Maehara

研究成果: ジャーナルへの寄稿学術誌査読


Purposes Delayed gastric emptying (DGE) after hepatectomy affects the quality of life of patients, although the causes and related conditions have not been investigated. This study evaluated the relationship between hepatectomy and DGE by the objective assessment of gastric emptying (GE). Methods Nineteen patients who underwent major hepatectomy were prospectively enrolled in the study. Their GE was studied using the 13C-acetic acid breath test before and after hepatectomy. The results of the GE analysis were correlated with the postoperative course after hepatectomy. Results Clinically evident DGE, which was defined as the inability to take in an appropriate amount of solid food orally by postoperative day 14, was not found in these patients, but the gastric half-emptying times before and after hepatectomy were 20.2 ± 9.7 and 28.6 ± 12.2 min, respectively (P = 0.01). The GE time was significantly delayed in patients aged ≥41 years, or who underwent right hemihepatectomy. Conclusions Gastric emptying was significantly inhibited in patients who underwent major hepatectomy, and aging and a right-sided hemihepatectomy may be related to the development of DGE.

ジャーナルSurgery today
出版ステータス出版済み - 11月 2012

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