Association between Axial Length and Myopic Maculopathy: The Hisayama Study

Sawako Hashimoto, Miho Yasuda, Kohta Fujiwara, Emi Ueda, Jun Hata, Yoichiro Hirakawa, Toshiharu Ninomiya, Koh hei Sonoda

研究成果: ジャーナルへの寄稿記事

抄録

Purpose: To assess the association between axial length (AL) and the prevalence of myopic maculopathy in a general Japanese population. Design: Population-based cross-sectional study. Participants: A total of 2790 Hisayama residents 40 years of age or older who consented to participate and had available data of AL and fundus photographs for the right eyes were enrolled in this study. Methods: Myopic maculopathy was defined as the presence of diffuse chorioretinal atrophy, patchy chorioretinal atrophy, or macular degeneration. The optimal cutoff values of axial length for identifying myopic maculopathy were estimated from the receiver operating characteristic curve. The odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using a logistic regression analysis. Main Outcome Measures: Odds ratios of AL for prevalent myopic maculopathy and the optimal cutoff values of AL for detecting myopic maculopathy. Results: Longer AL was associated significantly with prevalence of myopic maculopathy in both genders. The optimal cutoff values of AL for identifying myopic maculopathy were 25.9 mm in men and 25.3 mm in women. Participants with ALs of these values or longer showed a significantly higher OR for myopic maculopathy than those with AL of less than these values (men: OR, 21.23; 95% CI, 8.74–51.57; women: OR, 38.49; 95% CI, 18.03–86.49). Conclusions: The present study found that there was a positive association between AL and the likelihood of myopic maculopathy, and the cutoff levels of AL for identifying myopic maculopathy were 25.9 mm in men and 25.3 mm in women. Our findings suggest that patients with AL close to or longer than these values should undergo intensive treatment and detailed ophthalmic follow-up.

元の言語英語
ページ(範囲)867-873
ページ数7
ジャーナルOphthalmology Retina
3
発行部数10
DOI
出版物ステータス出版済み - 10 2019

Fingerprint

Odds Ratio
Confidence Intervals
Atrophy
Macular Degeneration
ROC Curve
Population
Cross-Sectional Studies
Logistic Models
Regression Analysis
Outcome Assessment (Health Care)
Therapeutics

All Science Journal Classification (ASJC) codes

  • Ophthalmology

これを引用

Association between Axial Length and Myopic Maculopathy : The Hisayama Study. / Hashimoto, Sawako; Yasuda, Miho; Fujiwara, Kohta; Ueda, Emi; Hata, Jun; Hirakawa, Yoichiro; Ninomiya, Toshiharu; Sonoda, Koh hei.

:: Ophthalmology Retina, 巻 3, 番号 10, 10.2019, p. 867-873.

研究成果: ジャーナルへの寄稿記事

@article{1480d79c469b40c4bded44317e4e4a0d,
title = "Association between Axial Length and Myopic Maculopathy: The Hisayama Study",
abstract = "Purpose: To assess the association between axial length (AL) and the prevalence of myopic maculopathy in a general Japanese population. Design: Population-based cross-sectional study. Participants: A total of 2790 Hisayama residents 40 years of age or older who consented to participate and had available data of AL and fundus photographs for the right eyes were enrolled in this study. Methods: Myopic maculopathy was defined as the presence of diffuse chorioretinal atrophy, patchy chorioretinal atrophy, or macular degeneration. The optimal cutoff values of axial length for identifying myopic maculopathy were estimated from the receiver operating characteristic curve. The odds ratios (ORs) and 95{\%} confidence intervals (CIs) were estimated using a logistic regression analysis. Main Outcome Measures: Odds ratios of AL for prevalent myopic maculopathy and the optimal cutoff values of AL for detecting myopic maculopathy. Results: Longer AL was associated significantly with prevalence of myopic maculopathy in both genders. The optimal cutoff values of AL for identifying myopic maculopathy were 25.9 mm in men and 25.3 mm in women. Participants with ALs of these values or longer showed a significantly higher OR for myopic maculopathy than those with AL of less than these values (men: OR, 21.23; 95{\%} CI, 8.74–51.57; women: OR, 38.49; 95{\%} CI, 18.03–86.49). Conclusions: The present study found that there was a positive association between AL and the likelihood of myopic maculopathy, and the cutoff levels of AL for identifying myopic maculopathy were 25.9 mm in men and 25.3 mm in women. Our findings suggest that patients with AL close to or longer than these values should undergo intensive treatment and detailed ophthalmic follow-up.",
author = "Sawako Hashimoto and Miho Yasuda and Kohta Fujiwara and Emi Ueda and Jun Hata and Yoichiro Hirakawa and Toshiharu Ninomiya and Sonoda, {Koh hei}",
year = "2019",
month = "10",
doi = "10.1016/j.oret.2019.04.023",
language = "English",
volume = "3",
pages = "867--873",
journal = "Ophthalmology Retina",
issn = "2468-7219",
publisher = "Elsevier Inc.",
number = "10",

}

TY - JOUR

T1 - Association between Axial Length and Myopic Maculopathy

T2 - The Hisayama Study

AU - Hashimoto, Sawako

AU - Yasuda, Miho

AU - Fujiwara, Kohta

AU - Ueda, Emi

AU - Hata, Jun

AU - Hirakawa, Yoichiro

AU - Ninomiya, Toshiharu

AU - Sonoda, Koh hei

PY - 2019/10

Y1 - 2019/10

N2 - Purpose: To assess the association between axial length (AL) and the prevalence of myopic maculopathy in a general Japanese population. Design: Population-based cross-sectional study. Participants: A total of 2790 Hisayama residents 40 years of age or older who consented to participate and had available data of AL and fundus photographs for the right eyes were enrolled in this study. Methods: Myopic maculopathy was defined as the presence of diffuse chorioretinal atrophy, patchy chorioretinal atrophy, or macular degeneration. The optimal cutoff values of axial length for identifying myopic maculopathy were estimated from the receiver operating characteristic curve. The odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using a logistic regression analysis. Main Outcome Measures: Odds ratios of AL for prevalent myopic maculopathy and the optimal cutoff values of AL for detecting myopic maculopathy. Results: Longer AL was associated significantly with prevalence of myopic maculopathy in both genders. The optimal cutoff values of AL for identifying myopic maculopathy were 25.9 mm in men and 25.3 mm in women. Participants with ALs of these values or longer showed a significantly higher OR for myopic maculopathy than those with AL of less than these values (men: OR, 21.23; 95% CI, 8.74–51.57; women: OR, 38.49; 95% CI, 18.03–86.49). Conclusions: The present study found that there was a positive association between AL and the likelihood of myopic maculopathy, and the cutoff levels of AL for identifying myopic maculopathy were 25.9 mm in men and 25.3 mm in women. Our findings suggest that patients with AL close to or longer than these values should undergo intensive treatment and detailed ophthalmic follow-up.

AB - Purpose: To assess the association between axial length (AL) and the prevalence of myopic maculopathy in a general Japanese population. Design: Population-based cross-sectional study. Participants: A total of 2790 Hisayama residents 40 years of age or older who consented to participate and had available data of AL and fundus photographs for the right eyes were enrolled in this study. Methods: Myopic maculopathy was defined as the presence of diffuse chorioretinal atrophy, patchy chorioretinal atrophy, or macular degeneration. The optimal cutoff values of axial length for identifying myopic maculopathy were estimated from the receiver operating characteristic curve. The odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using a logistic regression analysis. Main Outcome Measures: Odds ratios of AL for prevalent myopic maculopathy and the optimal cutoff values of AL for detecting myopic maculopathy. Results: Longer AL was associated significantly with prevalence of myopic maculopathy in both genders. The optimal cutoff values of AL for identifying myopic maculopathy were 25.9 mm in men and 25.3 mm in women. Participants with ALs of these values or longer showed a significantly higher OR for myopic maculopathy than those with AL of less than these values (men: OR, 21.23; 95% CI, 8.74–51.57; women: OR, 38.49; 95% CI, 18.03–86.49). Conclusions: The present study found that there was a positive association between AL and the likelihood of myopic maculopathy, and the cutoff levels of AL for identifying myopic maculopathy were 25.9 mm in men and 25.3 mm in women. Our findings suggest that patients with AL close to or longer than these values should undergo intensive treatment and detailed ophthalmic follow-up.

UR - http://www.scopus.com/inward/record.url?scp=85072589425&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85072589425&partnerID=8YFLogxK

U2 - 10.1016/j.oret.2019.04.023

DO - 10.1016/j.oret.2019.04.023

M3 - Article

AN - SCOPUS:85072589425

VL - 3

SP - 867

EP - 873

JO - Ophthalmology Retina

JF - Ophthalmology Retina

SN - 2468-7219

IS - 10

ER -