Association between HLA and Japanese patients with rheumatoid arthritis

Nobuo Ohta, Yoshi K. Nishimura, Kiyoaki Tanimoto, Yoshihiko Horiuchi, Chiyuki Abe, Yuichi Shiokawa, Tohru Abe, Makoto Katagiri, Takashi Yoshiki, Takehiko Sasazuki

研究成果: Contribution to journalArticle査読

120 被引用数 (Scopus)

抄録

Japanese patients with rheumatoid arthritis (RA) were observed to have a statistical association with HLA-DR4, MT3. Strong association between the clinical severity of RA and HLA was also observed. Male patients had a stronger association with HLA than female patients. Males are more resistant to RA than females. This suggested that the threshold of liability for RA is higher in males than in females. Japanese patients with RA with systemic vasculitis were negative for HLA-Bw44 and had antilymphocytotoxic autoantibody, indicating that RA with systemic vasculities is different in etiology from RA without systemic vasculities.

本文言語英語
ページ(範囲)123-132
ページ数10
ジャーナルHuman Immunology
5
2
DOI
出版ステータス出版済み - 10 1982
外部発表はい

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology

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