Association of retinal thickness and optic disc-to-fovea angle to axial length of young healthy eyes

Takehiro Yamashita, Taiji Sakamoto, Hiroto Terasaki, Minoru Tanaka, Yuya Kii, Eisuke Uchino, Toshio Hisatomi, Kumiko Nakao

研究成果: ジャーナルへの寄稿学術誌査読

7 被引用数 (Scopus)

抄録

Aim: To determine the relationship between the axial length (AL) and the retinal thickness in the posterior pole and to the optic disc-to-fovea (ODF) angle of healthy eyes. Procedures: A prospective, observational cross-sectional study (registration number, UMIN000006040) of 64 healthy right eyes (mean age 26.0±4.5 years) was performed. The thickness of the 64 areas within the central 24° area were measured in the Spectralis spectral domain–optical coherent tomographic images obtained by posterior pole scans. Each area was 3°×3°. The ODF angle was measured in each fundus photograph. The relationships between the AL and the retinal thickness of each of the 64 areas and the ODF angle were investigated by linear regression analyses. Results: The mean AL was 25.0±1.3 mm and the mean ODF angle was 17.2°±1.0°. The average retinal thickness of the four areas around the fovea was constant and not significantly correlated with the AL. However, the retinal thicknesses of 54 of the other 60 areas were significantly and negatively correlated with the AL (R=-0.25 to -0.56, P<0.05). The ODF angle was also constant and not significantly correlated with the AL (R=-0.17, P=0.19). Conclusion: The lack of significant correlations between the AL and the retinal thicknesses of the central 6° or the ODF angle suggests that there might be some feedback system to keep the central retinal thickness and ODF angle constant regardless of an elongation of the AL.

本文言語英語
ページ(範囲)2235-2241
ページ数7
ジャーナルClinical Ophthalmology
9
DOI
出版ステータス出版済み - 11月 27 2015
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 眼科学

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