Asymmetric Hydrogenation of Azaindoles: Chemo- and Enantioselective Reduction of Fused Aromatic Ring Systems Consisting of Two Heteroarenes

Yusuke Makida, Masahiro Saita, Takahiro Kuramoto, Kentaro Ishizuka, Ryoichi Kuwano

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

抄録

High enantioselectivity was achieved for the hydrogenation of azaindoles by using the chiral catalyst, which was prepared from [Ru(η3-methallyl)2(cod)] and a trans-chelating bis(phosphine) ligand (PhTRAP). The dearomative reaction exclusively occurred on the five-membered ring, thus giving the corresponding azaindolines with up to 97:3 enantiomer ratio.

元の言語英語
ページ(範囲)11859-11862
ページ数4
ジャーナルAngewandte Chemie - International Edition
55
発行部数39
DOI
出版物ステータス出版済み - 1 1 2016

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phosphine
Enantiomers
Enantioselectivity
Chelation
Hydrogenation
Ligands
Catalysts

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

これを引用

Asymmetric Hydrogenation of Azaindoles : Chemo- and Enantioselective Reduction of Fused Aromatic Ring Systems Consisting of Two Heteroarenes. / Makida, Yusuke; Saita, Masahiro; Kuramoto, Takahiro; Ishizuka, Kentaro; Kuwano, Ryoichi.

:: Angewandte Chemie - International Edition, 巻 55, 番号 39, 01.01.2016, p. 11859-11862.

研究成果: ジャーナルへの寄稿記事

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