(Chemical Equation Presented) Taking the silyl group a step further: An unprecedented rearrangement in an anion derived from an allyloxysilane occurs by a [1,4] shift of the silyl group (see scheme). The asymmetric synthesis of enantiomerically enriched γ-functionalized allylsilanes with Si stereocenters can be accomplished with this retro-[1,4] Brook rearrangement. E = electrophile.
!!!All Science Journal Classification (ASJC) codes
- 化学 (全般)