Atopic dermatitis-immunological abnormality and its background

Masutaka Furue

研究成果: ジャーナルへの寄稿総説査読

22 被引用数 (Scopus)

抄録

The production of IgE is mainly regulated by cognate and/or non-cognate interaction between B cells and T cells. Two types of helper T cells are recognized in the murine system, Th1 and Th2, by the type of cytokine they produce. Several lines of evidence disclosed that unbalanced generation of Th2 Th1-like cells occurs in atopic disorders, such as atopic dermatitis, in which a high level of serum IgE is found in the majority of patients. Analysis of skin-derived immunocompetent cells, such as Langerhans cells and T cells, has provided us with a new understanding of the pathophysiology of atopic dermatitis. The recent progress in immunological aspects of atopic dermatitis is reviewed.

本文言語英語
ページ(範囲)159-168
ページ数10
ジャーナルJournal of Dermatological Science
7
3
DOI
出版ステータス出版済み - 6月 1994
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 生化学
  • 分子生物学
  • 皮膚病学

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