Augmentation of antigen-specific cytotoxicity by concanavalin A at the peak of response to tumor allografts

Yoshinori Shimamoto; Kikuo Nomoto; Kazuto Taniguchi; Chiharu Kubo

doi:10.1016/0008-8749(79)90329-0

Augmentation of antigen-specific cytotoxicity by concanavalin A at the peak of response to tumor allografts

Yoshinori Shimamoto, Kikuo Nomoto, Kazuto Taniguchi, Chiharu Kubo

研究成果: Contribution to journal › Article › 査読

抄録

Antigen-specific cytotoxicity was augmented 24 hr after in vivo or in vitro treatment with concanavalin A at approximately the peak of response to allografted EL-4 cells. Such augmentation appears to require protein synthesis but not cell division. The augmentation may be ascribed to enhanced expression of cytotoxic activity of performed effector T cells rather than an increase in the number of effector cells.

本文言語	英語
ページ（範囲）	204-210
ページ数	7
ジャーナル	Cellular Immunology
巻	47
号	1
DOI	https://doi.org/10.1016/0008-8749(79)90329-0
出版ステータス	出版済み - 9 15 1979
外部発表	はい

All Science Journal Classification (ASJC) codes

免疫学

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10.1016/0008-8749(79)90329-0

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abstract = "Antigen-specific cytotoxicity was augmented 24 hr after in vivo or in vitro treatment with concanavalin A at approximately the peak of response to allografted EL-4 cells. Such augmentation appears to require protein synthesis but not cell division. The augmentation may be ascribed to enhanced expression of cytotoxic activity of performed effector T cells rather than an increase in the number of effector cells.",

author = "Yoshinori Shimamoto and Kikuo Nomoto and Kazuto Taniguchi and Chiharu Kubo",

note = "Funding Information: This work was supported by Grants-in-Aid Science and Culture and the Ministry of Health",

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AU - Shimamoto, Yoshinori

AU - Nomoto, Kikuo

AU - Taniguchi, Kazuto

AU - Kubo, Chiharu

N1 - Funding Information: This work was supported by Grants-in-Aid Science and Culture and the Ministry of Health

PY - 1979/9/15

Y1 - 1979/9/15

N2 - Antigen-specific cytotoxicity was augmented 24 hr after in vivo or in vitro treatment with concanavalin A at approximately the peak of response to allografted EL-4 cells. Such augmentation appears to require protein synthesis but not cell division. The augmentation may be ascribed to enhanced expression of cytotoxic activity of performed effector T cells rather than an increase in the number of effector cells.

AB - Antigen-specific cytotoxicity was augmented 24 hr after in vivo or in vitro treatment with concanavalin A at approximately the peak of response to allografted EL-4 cells. Such augmentation appears to require protein synthesis but not cell division. The augmentation may be ascribed to enhanced expression of cytotoxic activity of performed effector T cells rather than an increase in the number of effector cells.

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Augmentation of antigen-specific cytotoxicity by concanavalin A at the peak of response to tumor allografts

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