Autism spectrum disorder

Hidetoshi Takahashi, Yoko Kamio, Shozo Tobimatsu

研究成果: 書籍/レポート タイプへの寄稿

抄録

Autism spectrum disorder (ASD) is a set of heterogeneous neurodevelopmental conditions characterized by early-onset difficulties in social communication and unusually restricted, repetitive behavior and interests. There has been substantial recent research on ASD. Magnetoencephalography (MEG) is used in ASD research for its noninvasive nature of recordings and for its excellent temporal and spatial resolution. The number of MEG-based ASD studies in children is increasing with larger study groups. Furthermore, the analyses are becoming more sophisticated. Research over the last several decades using MEG has identified consistent atypical electrophysiological signatures of ASD, indicating common neural circuit disruptions, such as reduced long-range resting-state neural connectivity. In addition, auditory processing MEG signatures, such as middle-latency response (M50/M100) and gamma-band oscillatory activity, hold particular promise in the study and treatment of ASD and as candidate biomarkers of ASD. With the development of MEG customized for a child’s head, some studies even include children younger than 3 years of age. Thus, future studies investigating these MEG signatures across developmental stages are expected to reveal the underlying neurobiology of ASD and may uncover new avenues of treatments for ASD.

本文言語英語
ホスト出版物のタイトルClinical Applications of Magnetoencephalography
出版社Springer Japan
ページ247-274
ページ数28
ISBN(電子版)9784431557296
ISBN(印刷版)9784431557289
DOI
出版ステータス出版済み - 1月 1 2016

!!!All Science Journal Classification (ASJC) codes

  • 医学(全般)
  • 神経科学(全般)

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