Automated spectroscopic imaging of oxygen saturation in human retinal vessels

D. Nakamura, S. Sueda, N. Matsuoka, Y. Yoshinaga, H. Enaida, T. Okada, T. Ishibashi

研究成果: Contribution to journalConference article査読

3 被引用数 (Scopus)


A new automatic visualization procedure for the oxygen saturation imaging from multi-spectral imaging of human retinal vessels has been proposed. Two-wavelength retinal fundus images at 545 and 560 nm, which were oxygen insensitive and oxygen sensitive, respectively, were captured by CCD cameras simultaneously through a beam splitter and interference filters. We applied a morphological processing technique to presume a distribution of incident light including the vessel parts and an optical density (OD) image of each wavelength image. And the OD ratio (OD560/OD545) image was calculated as a relative indicator of oxygen saturation. Furthermore, processing of line convergence index filter was adopted to identify the retinal vessels. Clear difference between retinal arteries and veins was observed in the automated imaging method. In addition, the decrease of oxygen saturation in the retinal artery without breathing could be monitored by the ODR. This method is possible to be applied to real-time monitoring for oxygen saturation of retinal vessels.

ジャーナルProgress in Biomedical Optics and Imaging - Proceedings of SPIE
出版ステータス出版済み - 2009
イベントOphthalmic Technologies XIX - San Jose, CA, 米国
継続期間: 1 24 20091 26 2009

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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