Autonomic innervation of the intestine from a baby with megacystis microcolon intestinal hypoperistalsis syndrome: I. Immunohistochemical study

T. Taguchi, K. Ikeda, T. Shono, S. Goto, M. Kubota, T. Kawana, R. Hirose, T. Toyohara

研究成果: Contribution to journalArticle査読

50 被引用数 (Scopus)

抄録

A typical case of megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS) is reported. The patient, an infant girl, was fed only by total intravenous nutrition and is now 3 years old. The distribution of several gut peptides was examined in the resected small intestine using an immunohistochemical method. Vasoactive intestinal polypeptide (VIP) and peptide histidine methionin (PHM)-containing nerve fibers were decreased; however, substance P- and leucine enkephalin (Leu-ENK)-containing fibers were increased. The imbalance between several kinds of gut peptides might be one of the causes of aperistalsis in MMIHS. This is the first report about the gut peptides of MMIHS.

本文言語英語
ページ(範囲)1264-1266
ページ数3
ジャーナルJournal of Pediatric Surgery
24
12
DOI
出版ステータス出版済み - 12 1989

All Science Journal Classification (ASJC) codes

  • 外科
  • 小児科学、周産期医学および子どもの健康

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