Baseline characterization of patients aged 70 years and above with hepatocellular carcinoma

Makoto Nakamuta, Shusuke Morizono, Motoyuki Kohjima, Kazuhiro Kotoh, Munechika Enjoji

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)

抄録

Aim: To characterize the baseline profiles of patients aged 70 years and above with hepatocellular carcinoma (HCC). Methods: A series of 127 consecutive patients with HCC were enrolled between 2000 and 2004, and none of them had been diagnosed as having HCC previously. Baseline profiles, including parameters of hepatic function such as serum transaminase and prothrombin time [PT (% activity)] were compared between patients aged ≥70 and <70 years. Results: Patients ≥70 years old showed significantly lower levels of aspartate aminotransferase (P = 0.04) and alanine aminotransferase (P = 0.01), and significantly higher PTs (P = 0.04) and platelet counts (P = 0.02). Concomitantly, among ≥70-year-old patients, HCC was more common in non-cirrhotics, whereas among patients <70 years old, HCC was more common in cirrhotics. There was no significant difference between the groups in the number or size of tumors. Conclusion: Older HCC patients showed less inflammation and better preservation of hepatic function, indicating that not only cirrhotic patients but also non-cirrhotic patients should be considered as a high-risk group among the elderly.

元の言語英語
ページ(範囲)7512-7514
ページ数3
ジャーナルWorld Journal of Gastroenterology
11
発行部数47
DOI
出版物ステータス出版済み - 12 21 2005

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Hepatocellular Carcinoma
Liver
Prothrombin Time
Aspartate Aminotransferases
Transaminases
Alanine Transaminase
Platelet Count
Inflammation
Serum
Neoplasms

All Science Journal Classification (ASJC) codes

  • Gastroenterology

これを引用

Baseline characterization of patients aged 70 years and above with hepatocellular carcinoma. / Nakamuta, Makoto; Morizono, Shusuke; Kohjima, Motoyuki; Kotoh, Kazuhiro; Enjoji, Munechika.

:: World Journal of Gastroenterology, 巻 11, 番号 47, 21.12.2005, p. 7512-7514.

研究成果: ジャーナルへの寄稿記事

Nakamuta, Makoto ; Morizono, Shusuke ; Kohjima, Motoyuki ; Kotoh, Kazuhiro ; Enjoji, Munechika. / Baseline characterization of patients aged 70 years and above with hepatocellular carcinoma. :: World Journal of Gastroenterology. 2005 ; 巻 11, 番号 47. pp. 7512-7514.
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AU - Enjoji, Munechika

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