Basic properties of apatite cement containing carbonate apatite and its resorption by cultured osteoclasts

Y. Miyamoto, T. Toh, T. Yuasa, M. Takechi, Y. Momota, M. Nagayama, Kunio Ishikawa, K. Suzuki

研究成果: ジャーナルへの寄稿Conference article

2 引用 (Scopus)

抄録

Apatite cement (AC) has received much attention as a new reconstructive material for bony defects because AC transforms to hydroxyapatite (HAP) and shows excellent tissue response and osteoconductivity. In addition, AC has been reported to be partly replaced with bone, although the process takes a long time. The aim of this study, therefore, is to fabricate bone-replacing apatite cement by converting AC to be easily resorbed by osteoclasts. For this purpose, NaHCO3 was added into the AC component. The amount of CO3 incorporated into the set AC increased with the amount of added NaHCO3. B-type carbonate apatite (CO3-AP) was formed in the set AC added NaHCO3. The dissolution rate of the set AC in weak acid, pH 5.5, increased with NaHCO3. The number of resorption pits and the resorbed area by cultured osteoclasts increased with added CO3 content. The resorbed area on 4% CO3-added-AC was twice as much as that of carbonate-free-AC. The results suggested that CO3-AP-formed AC would be easily resorbed by osteoclasts.

元の言語英語
ページ(範囲)829-832
ページ数4
ジャーナルKey Engineering Materials
192-195
出版物ステータス出版済み - 1 1 2001
外部発表Yes
イベント13th international Symposium on Ceramics in Medicine (BIOCERAMICS) - Bologna, Italy
継続期間: 11 22 200011 26 2000

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Apatites
Apatite
Carbonates
Cements
Osteoclasts
carboapatite
Bone
Bone cement
Durapatite
Hydroxyapatite
Dissolution

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

これを引用

Miyamoto, Y., Toh, T., Yuasa, T., Takechi, M., Momota, Y., Nagayama, M., ... Suzuki, K. (2001). Basic properties of apatite cement containing carbonate apatite and its resorption by cultured osteoclasts. Key Engineering Materials, 192-195, 829-832.

Basic properties of apatite cement containing carbonate apatite and its resorption by cultured osteoclasts. / Miyamoto, Y.; Toh, T.; Yuasa, T.; Takechi, M.; Momota, Y.; Nagayama, M.; Ishikawa, Kunio; Suzuki, K.

:: Key Engineering Materials, 巻 192-195, 01.01.2001, p. 829-832.

研究成果: ジャーナルへの寄稿Conference article

Miyamoto, Y, Toh, T, Yuasa, T, Takechi, M, Momota, Y, Nagayama, M, Ishikawa, K & Suzuki, K 2001, 'Basic properties of apatite cement containing carbonate apatite and its resorption by cultured osteoclasts', Key Engineering Materials, 巻. 192-195, pp. 829-832.
Miyamoto Y, Toh T, Yuasa T, Takechi M, Momota Y, Nagayama M その他. Basic properties of apatite cement containing carbonate apatite and its resorption by cultured osteoclasts. Key Engineering Materials. 2001 1 1;192-195:829-832.
Miyamoto, Y. ; Toh, T. ; Yuasa, T. ; Takechi, M. ; Momota, Y. ; Nagayama, M. ; Ishikawa, Kunio ; Suzuki, K. / Basic properties of apatite cement containing carbonate apatite and its resorption by cultured osteoclasts. :: Key Engineering Materials. 2001 ; 巻 192-195. pp. 829-832.
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AU - Momota, Y.

AU - Nagayama, M.

AU - Ishikawa, Kunio

AU - Suzuki, K.

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