Bassiamide A, a new alkaloid from xero-halophyte Bassia indica Wight.

Ahmed Othman, Yhiya Amen, Masako Matsumoto, Maki Nagata, Kuniyoshi Shimizu

研究成果: Contribution to journalArticle査読

1 被引用数 (Scopus)


N-[(3-(3-methyl-1-oxo-butyl)amino)propyl]-3-(3,4-dihydroxyphenyl)prop-2-enamide (7), named ‘Bassiamide A’, a new alkaloid, together with six known compounds including one lignan (1) and five lignanamides (2–6), were isolated from the aerial parts of Bassia indica Wight. The study also reported an optimal separation of a rare occurring R-isomer lignanamide derivative (6) from a natural origin, in addition to its known corresponding S-isomer (5). Structures of isolated compounds were elucidated based on NMR spectroscopic data, HR-MS, and comparison with known related ones, and they were identified as syringaresinol (1), N-trans-feruloyl-3-methoxytyramine (2), N-trans-feruloyltyramine (3), S-(-)-N-trans-feruloyl normetanephrine (4), S-(-)-N-trans-feruloyl octopamine (5), R-(+)-N-trans-feruloyl octopamine (6). The isolated compounds were evaluated for their anti-acetylcholinesterase activity, and they showed weak inhibitory activity.

ジャーナルNatural Product Research
出版ステータス受理済み/印刷中 - 2021

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Plant Science
  • Organic Chemistry

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