Big bang in the evolution of extant malaria parasites

Toshiyuki Hayakawa, Richard Culleton, Hiroto Otani, Toshihiro Horii, Kazuyuki Tanabe

研究成果: ジャーナルへの寄稿学術誌査読

80 被引用数 (Scopus)

抄録

Malaria parasites (genus Plasmodium) infect all classes of terrestrial vertebrates and display host specificity in their infections. It is therefore assumed that malaria parasites coevolved intimately with their hosts. Here, we propose a novel scenario of malaria parasite-host coevolution. A phylogenetic tree constructed using the malaria parasite mitochondrial genome reveals that the extant primate, rodent, bird, and reptile parasite lineages rapidly diverged from a common ancestor during an evolutionary short time period. This rapid diversification occurred long after the establishment of the primate, rodent, bird, and reptile host lineages, which implies that host-switch events contributed to the rapid diversification of extant malaria parasite lineages. Interestingly, the rapid diversification coincides with the radiation of the mammalian genera, suggesting that adaptive radiation to new mammalian hosts triggered the rapid diversification of extant malaria parasite lineages.

本文言語英語
ページ(範囲)2233-2239
ページ数7
ジャーナルMolecular Biology and Evolution
25
10
DOI
出版ステータス出版済み - 10月 2008
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 生態、進化、行動および分類学
  • 分子生物学
  • 遺伝学

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