Biochemical switching device: biomimetic approach and application to neural network study

Masahiro Okamoto

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

抄録

There are many examples of enzymes that share substrates or cofactors in a cyclic manner. Techniques have been developed that use cyclic enzyme systems to assay quantitatively small amounts of biochemical substances (cofactor, substrate), however, only a few studies of the control of these systems have been published. The author previously showed with computer simulations that cyclic enzyme systems have the reliability of on-off types of operation (McCulloch-Pitts' neuronic equation) capable of storing short-memory, and the applicability for a switching circuit in a biocomputer. This paper introduces a unique switching mechanism of cyclic enzyme system (basic switching element), and next, building the integrated biochemical switching system being composed of the basic switching element, shows the physiological phenomenon termed 'selective elimination of synapses' generally produced as a result of low-frequency train of electrical stimuli to the synapses (Kuroda, Y. (1989) Neurochem. Int. 14, 309-319).

元の言語英語
ページ(範囲)109-127
ページ数19
ジャーナルJournal of Biotechnology
24
発行部数1
DOI
出版物ステータス出版済み - 6 1 1992

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Biomimetic Materials
Biomimetics
Enzymes
Neural networks
Synapses
Physiological Phenomena
Switching circuits
Switching systems
Substrates
Computer Simulation
Assays
Data storage equipment
Computer simulation

All Science Journal Classification (ASJC) codes

  • Biotechnology

これを引用

Biochemical switching device : biomimetic approach and application to neural network study. / Okamoto, Masahiro.

:: Journal of Biotechnology, 巻 24, 番号 1, 01.06.1992, p. 109-127.

研究成果: ジャーナルへの寄稿記事

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