Biochemical switching device: how to turn on (off) the switch

Masahiro Okamoto, Toshio Sakai, Katsuya Hayashi

研究成果: Contribution to journalArticle査読

7 被引用数 (Scopus)

抄録

We previously showed with computer simulations that cyclic enzyme systems have the reliability of ON-OFF types of operation (McCulloch-Pitts' neuronic equation) and the applicability for a switching circuit in a biocomputer. The switching time was inevitably determined in accordance with the difference in amount between two inputs of the system. This characteristic is, however, a disadvantage for practical use of a switching device; we need to improve the system in order for the switching time to optionally be changed. We shall present here how to turn on (off) the switch independently of the modes of two inputs. By introducing pulse perturbation, we could optionally set up the switching time of a cyclic enzyme system (biochemical switching device).

本文言語英語
ページ(範囲)155-162
ページ数8
ジャーナルBioSystems
22
2
DOI
出版ステータス出版済み - 1989

All Science Journal Classification (ASJC) codes

  • 統計学および確率
  • モデリングとシミュレーション
  • 生化学、遺伝学、分子生物学(全般)
  • 応用数学

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