Biological activities of extracts from different parts of two cultivars of Prunus persica 'akatsuki' and 'fastigiata'

Toshinori Nakagawa, Ahmed E. Allam, Koichiro Ohnuki, Kuniyoshi Shimizu

研究成果: Contribution to journalArticle査読

7 被引用数 (Scopus)

抄録

We investigated the antioxidant, anti-lipase and anti-dementia activities of peach (Prunus persica (L.) Batsch) fruit and its by-products. The ethanol extracts of branch showed relatively high activity in all biological activities. Then, the extract was fractionated, and eight compounds were isolated from the ethyl acetate fraction. Results showed 4,2',4'-trihydroxy-6'-methoxychalcone 4'-O-β-D-glucopyranoside (5) and quercetin 3-O-β-D-glucopyranoside (7) as newly identified compounds in P. persica. From the biological investigation, it was considered that quercetin 3-O-β-D-glucopyranoside (7) was the main active compound of antioxidant activity. The main active compound of anti-lipase activity in these was oleanolic acid (1). In addition, (+)-4'-O-methylcatechin (4), 4,2',4'- trihydroxy-6'-methoxychalcone 4'-O-β-D-glucopyranoside (5) and ferulic acid (6) were the main active compounds of anti-dementia activity with acetylcholinesterase inhibitory assay. The results obtained suggested that these active compounds from peach branches of P. persica could be exploited as natural antioxidants, anti-lipase and anti-dementia materials in the future.

本文言語英語
ページ(範囲)1293-1296
ページ数4
ジャーナルNatural product communications
13
10
DOI
出版ステータス出版済み - 10 2018

All Science Journal Classification (ASJC) codes

  • 薬理学
  • 植物科学
  • 創薬
  • 補完代替医療

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