Biological activity of optically active salithion and salioxon

Akinori Hirashima, Isaac Ishaaya, Ryohei Ueno, Yoshifumi Ichiyama, Shao Yong Wu, Morifusa Eto

研究成果: Contribution to journalArticle査読

22 被引用数 (Scopus)

抄録

Salioxon enantiomers were obtained from salithion enantiomers by MCPBA oxidation. The larvicidal and adulticidal activities of salithion enantiomers, and the anti-cholinesterase activity of salioxon enantiomers were determined on house flies. On larvae, the potency of (S)(-)-salithion (LC50 = 1.1 ppm) was about two-fold higher than the (R)(+)-enantiomer (LC50 = 2.1 ppm). A similar ratio was obtained when these compounds were applied topically to female adults. The relative potency of these enantiomers correlated well with the anti-cholinesterase activity of their respective oxidative enantiomers, (R)(+)-and (S)(-)-salioxon, which are assumed to have been formed after their application to the insects.

本文言語英語
ページ(範囲)175-178
ページ数4
ジャーナルAgricultural and Biological Chemistry
53
1
DOI
出版ステータス出版済み - 1 1989

All Science Journal Classification (ASJC) codes

  • 生化学、遺伝学、分子生物学(全般)
  • 農業および生物科学(全般)

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