複数回膜貫通型膜タンパク質の立体構造形成機構: バンド3タンパク質研究の成果より

阿部 義人, 濱崎 直孝

研究成果: ジャーナルへの寄稿記事

抄録

The conventional view of biosynthesis of membrane-embedded regions of integral membrane proteins is that the topology of membrane proteins is determined by signal-anchor sequences and signal-anchor sequence of type II. Here, we briefly review the evidence that in the case of integral membrane proteins with many membrane spans, and that the topology of membrane proteins is determined not only by signal-anchor sequences and signal-anchor sequence of type II, but also by signal-anchor sequence of type I. Evidence from band 3 study indicates that hydrophobic membrane peptide portions are not necessarily in contact with lipids in the membrane lipid bilayer and that even hydrophilic peptide portions are integrated into the lipid bilyar by the action of signal-anchor sequence of type I.
元の言語Japanese
ページ(範囲)4-9
ページ数6
ジャーナルBiophysics (Japan)
46
発行部数1
出版物ステータス出版済み - 1 25 2006

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Erythrocyte Anion Exchange Protein 1
Protein Sorting Signals
Membrane Proteins
Membranes
Lipids
Peptides
Lipid Bilayers
Membrane Lipids

これを引用

複数回膜貫通型膜タンパク質の立体構造形成機構 : バンド3タンパク質研究の成果より. / 阿部義人; 濱崎直孝.

:: Biophysics (Japan), 巻 46, 番号 1, 25.01.2006, p. 4-9.

研究成果: ジャーナルへの寄稿記事

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