Bleaching activity of 4-Phenyl-3-(substituted benzylthio)-4H-1,2,4-triazoles

Naotaka Yamada, Daisuke Kusano, Eiich Kuwano

研究成果: Contribution to journalArticle査読

4 被引用数 (Scopus)

抄録

A variety of 4-aryl- and 4-alkyl-3-(substituted benzylthio)-4H-1,2,4-triazoles were prepared and evaluated for their bleaching activity by the lettuce seedling test. Among the series of tested compounds, 4-(3-fluorophenyl)-3-(4-trifluoromethylbenzylthio)-4H-1,2,4-triazole (39) exhibited the highest bleaching activity, causing complete bleaching symptoms at 10 μM. In the dark condition, compound 39 inhibited the formation of such carotenoids as β-carotene, violaxanthin, neoxanthin and lutein, resulting in the formation of ζ-carotene, phytoene, phytofluene and β-zeacarotene, which were not detected in the untreated control. Treatment by compound 39 at 50 μM resulted in the amount of accumulated ζ-carotene being seven-fold higher than that of phytoene, phytofluene and β-zeacarotene. These results suggest that compound 39 might have interfered with desaturation, especially ζ-carotene desaturation, during carotenoid biosynthesis.

本文言語英語
ページ(範囲)1671-1676
ページ数6
ジャーナルBioscience, Biotechnology and Biochemistry
66
8
DOI
出版ステータス出版済み - 1 1 2002

All Science Journal Classification (ASJC) codes

  • バイオテクノロジー
  • 分析化学
  • 生化学
  • 応用微生物学とバイオテクノロジー
  • 分子生物学
  • 有機化学

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