Blood compatibility of organic-inorganic biomedical materials

Akiyoshi Osaka, Tomohiko Yoshioka, Takeshi Yabuta, Kanji Tsuru, Satoshi Hayakawa

研究成果: ジャーナルへの寄稿学術誌査読

抄録

Organic-inorganic hybrids involving Ti-O bonds were coated on stainless-steel (SUS316L) substrates. Tetraisopropoxide and titanium methacrylate triisopropoxide were employed as the major starting chemicals to provide TiO2-polydimethylsiloxane (PDMS) layers or organotitanium molecular thin layers, respectively. Fourier transform infrared spectra indicated that each layer contained Ti-O bonds in their structure. The obtained hybrid layers had little effects on the blood-clotting times such as active partial thromboplastin time and pro thrombin time. In addition, the number of adhered platelet on the TiO2-PDMS layers depended on the composition, while the organotitanium molecular thin layers suppressed fibrinogen adsorption compared with coating-free SUS 316L substrate.

本文言語英語
ページ(範囲)713-716
ページ数4
ジャーナルKey Engineering Materials
284-286
DOI
出版ステータス出版済み - 1月 1 2005
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 材料科学(全般)
  • 材料力学
  • 機械工学

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