Bone marrow cell response on carbonate apatite/PCL-coated α-tricalcium phosphate foam

Thi Bang Le, Xing Ling Shi, Ishikawa Kunio, Radzali Othman

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

抄録

The aim of this research work was to investigate in vitro effect of the carbonate apatite/poly(ε- caprolactone) (CO3Ap/PCL) on α-tricalcium phosphate (α-TCP) foam. α-TCP was produced by sintering CaCO3 and CaHPO4•2H2O at 1500°C for 5 h. It was then coated with CO3Ap/PCL (wt/wt=1/3) to improve both mechanical and biological properties. The initial cell attachment and proliferation of the bone marrow cells were carried out on the α-TCP and CO3Ap/PCL-coated α- TCP foams. The cell proliferation was calculated by AlamarBlue assay. The cells were able to migrate and proliferate well on both α-TCP and CO3Ap/PCL-coated α-TCP foams indicating an excellent biocompatibility. The incorporation of CO3Ap on the coating layer improved cellular attachment and accelerated proliferation. Thus, CO3Ap/PCL-coated α-TCP foam might be a promising candidate as implant material.

本文言語英語
ホスト出版物のタイトルFrontiers in Materials and Minerals Engineering
ページ7-12
ページ数6
DOI
出版ステータス出版済み - 1 8 2014
イベント5th Regional Conference on Materials Engineering and the 5th Regional Conference on Natural Resources and Materials 2013, RCM5 and RCNRM5 2013 - , マレーシア
継続期間: 1 22 20131 23 2013

出版物シリーズ

名前Advanced Materials Research
858
ISSN(印刷版)1022-6680

その他

その他5th Regional Conference on Materials Engineering and the 5th Regional Conference on Natural Resources and Materials 2013, RCM5 and RCNRM5 2013
Countryマレーシア
Period1/22/131/23/13

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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