Bone marrow-derived mesenchymal stem cells for regenerative medicine in craniofacial region

M. Miura, Y. Miura, W. Sonoyama, T. Yamaza, S. Gronthos, S. Shi

研究成果: Contribution to journalReview article査読

56 被引用数 (Scopus)

抄録

The craniofacial region contains many specified tissues including bone, cartilage, muscle, blood vessels and neurons. Defect or dysfunction of the craniofacial tissue after post-cancer ablative surgery, trauma, congenital malformations and progressive deforming skeletal diseases has a huge influence on the patient's life. Therefore, functional reconstruction of damaged tissues is highly expected. Bone marrow-derived mesenchymal stem cells (BMMSCs) are one of the most well characterized postnatal stem cell populations, and considered to be utilized for cell-based clinical therapies. Here, the current understanding and the potential applications in craniofacial tissue regeneration of BMMSCs are reviewed, and the current limitations and drawbacks are also discussed.

本文言語英語
ページ(範囲)514-522
ページ数9
ジャーナルOral Diseases
12
6
DOI
出版ステータス出版済み - 11 2006
外部発表はい

All Science Journal Classification (ASJC) codes

  • 耳鼻咽喉科学
  • 歯科学(全般)

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