Brain activation during processing of angry facial expressions in patients with alcohol dependency

Mi Sook Park; Sook Hee Kim; Sunju Sohn; Gap Jung Kim; Yeon Kyu Kim; Jin Hun Sohn

doi:10.1186/s40101-015-0046-6

Brain activation during processing of angry facial expressions in patients with alcohol dependency

Mi Sook Park, Sook Hee Kim, Sunju Sohn, Gap Jung Kim, Yeon Kyu Kim, Jin Hun Sohn

生理人類学

研究成果: Contribution to journal › Article › 査読

4 被引用数 (Scopus)

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Background: Alcoholism is associated with abnormal anger processing. The purpose of this study was to investigate brain regions involved in the evaluation of angry facial expressions in patients with alcohol dependency.Methods: Brain blood-oxygenation-level-dependent (BOLD) responses to angry faces were measured and compared between patients with alcohol dependency and controls.Results: During intensity ratings of angry faces, significant differences in BOLD were observed between patients with alcohol dependency and controls. That is, patients who were alcohol-dependent showed significantly greater activation in several brain regions, including the dorsal anterior cingulate cortex (dACC) and medial prefrontal cortex (MPFC).Conclusions: Following exposure to angry faces, abnormalities in dACC and MPFC activation in patients with alcohol dependency indicated possible inefficiencies or hypersensitivities in social cognitive processing.

本文言語	英語
論文番号	6
ジャーナル	Journal of physiological anthropology
巻	34
号	1
DOI	https://doi.org/10.1186/s40101-015-0046-6
出版ステータス	出版済み - 2015

All Science Journal Classification (ASJC) codes

人的要因と人間工学
生理学
整形外科およびスポーツ医学
人類学
公衆衛生学、環境および労働衛生
生理学（医学）

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10.1186/s40101-015-0046-6

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title = "Brain activation during processing of angry facial expressions in patients with alcohol dependency",

abstract = "Background: Alcoholism is associated with abnormal anger processing. The purpose of this study was to investigate brain regions involved in the evaluation of angry facial expressions in patients with alcohol dependency.Methods: Brain blood-oxygenation-level-dependent (BOLD) responses to angry faces were measured and compared between patients with alcohol dependency and controls.Results: During intensity ratings of angry faces, significant differences in BOLD were observed between patients with alcohol dependency and controls. That is, patients who were alcohol-dependent showed significantly greater activation in several brain regions, including the dorsal anterior cingulate cortex (dACC) and medial prefrontal cortex (MPFC).Conclusions: Following exposure to angry faces, abnormalities in dACC and MPFC activation in patients with alcohol dependency indicated possible inefficiencies or hypersensitivities in social cognitive processing.",

author = "Park, {Mi Sook} and Kim, {Sook Hee} and Sunju Sohn and Kim, {Gap Jung} and Kim, {Yeon Kyu} and Sohn, {Jin Hun}",

note = "Funding Information: This research paper is made possible through the help and support from Ms. Jihye Noh and Ms. Ji-Eun Park. I would like to thank Ms. Jihye Noh for her most support in order to conduct the fMRI experiment with alcoholic patients. Ms. Ji-Eun Park kindly read my paper and offered invaluable detailed advices on grammar, organization, and the theme of the paper. I would like to also thank to my participants who made this study possible. This work was supported by the National Research Foundation of Korea Grant funded by the Korean Government (No. NRF-2006-2005087). Publisher Copyright: {\textcopyright} 2015 Park et al.; licensee BioMed Central.",

year = "2015",

doi = "10.1186/s40101-015-0046-6",

language = "English",

volume = "34",

journal = "Journal of Physiological Anthropology",

issn = "1880-6791",

publisher = "Japan Society of Physiological Anthropology",

number = "1",

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AU - Park, Mi Sook

AU - Kim, Sook Hee

AU - Sohn, Sunju

AU - Kim, Gap Jung

AU - Kim, Yeon Kyu

AU - Sohn, Jin Hun

N1 - Funding Information: This research paper is made possible through the help and support from Ms. Jihye Noh and Ms. Ji-Eun Park. I would like to thank Ms. Jihye Noh for her most support in order to conduct the fMRI experiment with alcoholic patients. Ms. Ji-Eun Park kindly read my paper and offered invaluable detailed advices on grammar, organization, and the theme of the paper. I would like to also thank to my participants who made this study possible. This work was supported by the National Research Foundation of Korea Grant funded by the Korean Government (No. NRF-2006-2005087). Publisher Copyright: © 2015 Park et al.; licensee BioMed Central.

PY - 2015

Y1 - 2015

N2 - Background: Alcoholism is associated with abnormal anger processing. The purpose of this study was to investigate brain regions involved in the evaluation of angry facial expressions in patients with alcohol dependency.Methods: Brain blood-oxygenation-level-dependent (BOLD) responses to angry faces were measured and compared between patients with alcohol dependency and controls.Results: During intensity ratings of angry faces, significant differences in BOLD were observed between patients with alcohol dependency and controls. That is, patients who were alcohol-dependent showed significantly greater activation in several brain regions, including the dorsal anterior cingulate cortex (dACC) and medial prefrontal cortex (MPFC).Conclusions: Following exposure to angry faces, abnormalities in dACC and MPFC activation in patients with alcohol dependency indicated possible inefficiencies or hypersensitivities in social cognitive processing.

AB - Background: Alcoholism is associated with abnormal anger processing. The purpose of this study was to investigate brain regions involved in the evaluation of angry facial expressions in patients with alcohol dependency.Methods: Brain blood-oxygenation-level-dependent (BOLD) responses to angry faces were measured and compared between patients with alcohol dependency and controls.Results: During intensity ratings of angry faces, significant differences in BOLD were observed between patients with alcohol dependency and controls. That is, patients who were alcohol-dependent showed significantly greater activation in several brain regions, including the dorsal anterior cingulate cortex (dACC) and medial prefrontal cortex (MPFC).Conclusions: Following exposure to angry faces, abnormalities in dACC and MPFC activation in patients with alcohol dependency indicated possible inefficiencies or hypersensitivities in social cognitive processing.

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Brain activation during processing of angry facial expressions in patients with alcohol dependency

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