Brain activation during processing of angry facial expressions in patients with alcohol dependency

Mi Sook Park, Sook Hee Kim, Sunju Sohn, Gap Jung Kim, Yeon Kyu Kim, Jin Hun Sohn

研究成果: Contribution to journalArticle査読

4 被引用数 (Scopus)

抄録

Background: Alcoholism is associated with abnormal anger processing. The purpose of this study was to investigate brain regions involved in the evaluation of angry facial expressions in patients with alcohol dependency.Methods: Brain blood-oxygenation-level-dependent (BOLD) responses to angry faces were measured and compared between patients with alcohol dependency and controls.Results: During intensity ratings of angry faces, significant differences in BOLD were observed between patients with alcohol dependency and controls. That is, patients who were alcohol-dependent showed significantly greater activation in several brain regions, including the dorsal anterior cingulate cortex (dACC) and medial prefrontal cortex (MPFC).Conclusions: Following exposure to angry faces, abnormalities in dACC and MPFC activation in patients with alcohol dependency indicated possible inefficiencies or hypersensitivities in social cognitive processing.

本文言語英語
論文番号6
ジャーナルJournal of physiological anthropology
34
1
DOI
出版ステータス出版済み - 2015

All Science Journal Classification (ASJC) codes

  • 人的要因と人間工学
  • 生理学
  • 整形外科およびスポーツ医学
  • 人類学
  • 公衆衛生学、環境および労働衛生
  • 生理学(医学)

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