Calix[6]arene acetic acid extraction behavior and specificity with respect to nucleobases

Kojiro Shimojo, Tatsuya Oshima, Masahiro Goto

    研究成果: ジャーナルへの寄稿学術誌査読

    30 被引用数 (Scopus)

    抄録

    The extraction behavior of various nucleobases was investigated with a series of calixarene derivatives. A calix[6]arene acetic acid was found to extract around 80% of adenine from an aqueous phase, and showed the highest specificity for adenine among all the nucleobases tested. The important factors influencing the recognition properties of calixarene were discovered to be its cyclic structure, its cavity size, and the functional carboxylic acid groups. The carbonyl group and the position of the amino group in the guest molecules also affect the extraction efficiency. Calix[6]arene forms a stable 1:1 complex with adenine by entrapping it into the cavity. Adenine was readily recovered from the organic phase by contacting with a fresh acidic solution.

    本文言語英語
    ページ(範囲)163-171
    ページ数9
    ジャーナルAnalytica Chimica Acta
    521
    2
    DOI
    出版ステータス出版済み - 9月 13 2004

    !!!All Science Journal Classification (ASJC) codes

    • 分析化学
    • 生化学
    • 環境化学
    • 分光学

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