Cannabis, 21. Biotransformation of cannabinol to its glycosides by in vitro plant tissue

Hiroyuki Tanaka, Satoshi Morimoto, Yukihiro Shoyama

研究成果: ジャーナルへの寄稿記事

14 引用 (Scopus)

抜粋

A marijuana compound, cannabinol [1], was converted to two metabolites using in vitro tissue of Pinellia ternata. The structures of the metabolites were determined to be cannabinol-O-β-d-glucopyranoside [2] and 9′-hydroxycannabinol-O-β-d-glucopyranoside [3] by 1H nmr and 13C nmr. From the time course experiments, 1 was absorbed rapidly in the tissues and glycosylated. Hydroxylation at the pentyl group occurred, and its metabolite was secreted in the medium.

元の言語英語
ページ(範囲)2068-2072
ページ数5
ジャーナルJournal of Natural Products
56
発行部数12
DOI
出版物ステータス出版済み - 12 1993

    フィンガープリント

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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