Cannabis 25, biotransformation of cannabidiol and cannabidiolic acid by Pinellia ternata tissue segments

Hiroyuki Tanaka, Ryuji Takahashi, Satoshi Morimoto, Yukihiro Shoyama

研究成果: ジャーナルへの寄稿記事

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抜粋

Two marihuana constituents, cannabidiol (1) and cannabidiolic acid (4) were each converted mainly to two metabolites using tissue segments of Pinellia ternata tuber. The structures of the metabolites formed from 1 were determined to be 1-0-β-D-glucopyranoside and 1-0-β-D- diglucopyranoside by 1H nmr, 13C nmr and fabms. Those from 4 were determined as 4- 0- β-D- glucopyranoside and 10'-hydroxyl 4-0- βD-glucopyranoside. In time course experiments, 1 was absorbed rapidly by the tissues and glucosylated. Hydroxylation subsequent to the glucosylation occurred at the pentyl group in 4.

元の言語英語
ページ(範囲)819-823
ページ数5
ジャーナルPlant Cell Reports
15
発行部数11
DOI
出版物ステータス出版済み - 1 1 1996

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All Science Journal Classification (ASJC) codes

  • Agronomy and Crop Science
  • Plant Science

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