Carbon ion radiotherapy: Clinical experiences at national institute of radiological science (NIRS)

Tohru Okada, Tadashi Kamada, Hiroshi Tsuji, Jun Etsu Mizoe, Masayuki Baba, Shingo Kato, Shigeru Yamada, Shinji Sugahara, Shigeo Yasuda, Naoyoshi Yamamoto, Reiko Imai, Azusa Hasegawa, Hiroshi Imada, Hiroki Kiyohara, Kenichi Jingu, Makoto Shinoto, Hirohiko Tsujii

研究成果: Contribution to journalReview article査読

124 被引用数 (Scopus)

抄録

In June 1994, the world's first clinical center offering carbon ion radiotherapy opened at the National Institute of Radiological Science (NIRS), Japan. Among several types of ion species, carbon ions were chosen for cancer therapy because they were judged to have the most optimal properties in terms of superior physical and biological characteristics. As of March 2010, 5,196 patients have been registered for carbon ion radiotherapy. Clinical results have shown that carbon ion radiotherapy has the potential to provide a sufficient radiation dose to the tumor, while having acceptable morbidity in the surrounding normal tissues. Tumors that appear to respond favorably to carbon ions include locally advanced tumors as well as histologically non-squamous cell tumor types such as adenocarcinoma, adenoid cystic carcinoma, malignant melanoma, hepatoma, and bone/soft tissue sarcoma. By taking advantage of the unique properties of carbon ions, treatment with small fractions within a short treatment period has been successfully carried out for a variety of tumors. This means that carbon ion radiotherapy can offer treatment for larger numbers of patients than is possible with other modalities over the same time period.

本文言語英語
ページ(範囲)355-364
ページ数10
ジャーナルJournal of radiation research
51
4
DOI
出版ステータス出版済み - 2010

All Science Journal Classification (ASJC) codes

  • 放射線
  • 放射線学、核医学およびイメージング
  • 健康、毒物学および変異誘発

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