Carboquone alters the protein synthesis of Chinese hamster V79 cell

Y. Maehara, H. Anai, H. Kusumoto, K. Sugimachi

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

抄録

The effect of carboquone (CQ) on protein synthesis in Chinese hamster V79 cells was determined. While the syntheses of higher molecular weight proteins decreased, the relative level of a 43-kilodalton (kd) protein increased following exposure to CQ at the concentration of 0.5 μg/ml, in a time-related fashion, determined using one-dimensional gel electrophoresis. Using two-dimensional gel electrophoresis, the 43-kd protein may be actin protein, and the syntheses of another two proteins of 8.5/45 and 48/270 (designated isoelectric point/molecular weight, kd) were increased in the CQ-treated V79 cells. These changes of the proteins induced by CQ in V79 cells were noted in HeLa cells. Three CQ-induced proteins are candidates for the elucidation of the antineoplastic effect of CQ.

元の言語英語
ページ(範囲)253-256
ページ数4
ジャーナルOncology
44
発行部数4
DOI
出版物ステータス出版済み - 1 1 1987

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Carbazilquinone
Cricetulus
Proteins
Molecular Weight
Electrophoresis, Gel, Two-Dimensional
Isoelectric Point
HeLa Cells
Antineoplastic Agents
Electrophoresis
Actins
Gels

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

これを引用

Maehara, Y., Anai, H., Kusumoto, H., & Sugimachi, K. (1987). Carboquone alters the protein synthesis of Chinese hamster V79 cell. Oncology, 44(4), 253-256. https://doi.org/10.1159/000226489

Carboquone alters the protein synthesis of Chinese hamster V79 cell. / Maehara, Y.; Anai, H.; Kusumoto, H.; Sugimachi, K.

:: Oncology, 巻 44, 番号 4, 01.01.1987, p. 253-256.

研究成果: ジャーナルへの寄稿記事

Maehara, Y, Anai, H, Kusumoto, H & Sugimachi, K 1987, 'Carboquone alters the protein synthesis of Chinese hamster V79 cell', Oncology, 巻. 44, 番号 4, pp. 253-256. https://doi.org/10.1159/000226489
Maehara Y, Anai H, Kusumoto H, Sugimachi K. Carboquone alters the protein synthesis of Chinese hamster V79 cell. Oncology. 1987 1 1;44(4):253-256. https://doi.org/10.1159/000226489
Maehara, Y. ; Anai, H. ; Kusumoto, H. ; Sugimachi, K. / Carboquone alters the protein synthesis of Chinese hamster V79 cell. :: Oncology. 1987 ; 巻 44, 番号 4. pp. 253-256.
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