Cardiac magnetic resonance performs better in the detection of functionally significant coronary artery Stenosis compared to single-photon emission computed Tomography and Dobutamine stress echocardiography

Kiwamu Kamiya, Mamoru Sakakibara, Naoya Asakawa, Shiro Yamada, Takashi Yoshitani, Hiroyuki Iwano, Hiroshi Komatsu, Masanao Naya, Satoru Chiba, Satoshi Yamada, Osamu Manabe, Yasuka Kikuchi, Noriko Oyama-Manabe, Koji Oba, Hiroyuki Tsutsui

研究成果: Contribution to journalArticle査読

18 被引用数 (Scopus)

抄録

Background: Fractional flow reserve (FFR) measured on catheterization is now widely used for the diagnosis of functional myocardial ischemia in patients with coronary artery disease (CAD). FFR, however, is invasive and carries potential procedural complications. Therefore, the aim of this study was to compare the diagnostic capability in functionally significant stenosis identified on FFR, between cardiac magnetic resonance myocardial perfusion imaging (CMR-MPI), single-photon emission computed tomography MPI (SPECT-MPI), and dobutamine stress echocardiography (DSE) in patients with CAD.

Methods and Results: A total of 25 patients who had at least 1 angiographic stenosis ≥50% on coronary angiography was studied. CMR-MPI, SPECT-MPI and DSE were done before FFR measurement. FFR was measured in all 3 major epicardial coronary arteries. Out of 71 vascular territories excluding 4 territories due to inadequate imaging, 29 (41%) had FFR <0.80. The sensitivity of CMR-MPI was significantly higher than that of SPECT-MPI and DSE (P=0.02 and P=0.001, respectively). The area under the receiver operating characteristic curve (AUC) for CMR-MPI (AUC, 0.92) was significantly greater than for SPECT-MPI (AUC, 0.73; P=0.006) and DSE (AUC, 0.69; P<0.001).

Conclusions: CMR-MPI performed well in the detection of functionally significant stenosis defined according to FFR, and had the highest diagnostic sensitivity among the 3 modalities tested in patients with CAD.

本文言語英語
ページ(範囲)2468-2476
ページ数9
ジャーナルCirculation Journal
78
10
DOI
出版ステータス出版済み - 2014
外部発表はい

All Science Journal Classification (ASJC) codes

  • 循環器および心血管医学

フィンガープリント

「Cardiac magnetic resonance performs better in the detection of functionally significant coronary artery Stenosis compared to single-photon emission computed Tomography and Dobutamine stress echocardiography」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル