Cardiovascular and metabolic diseases comorbid with psoriasis: Beyond the skin

Masutaka Furue, Gaku Tsuji, Takahito Chiba, Takafumi Kadono

研究成果: Contribution to journalReview article

19 引用 (Scopus)

抜粋

A close association of systemic inflammation with cardiovascular diseases and metabolic syndrome is recently a popular topic in medicine. Psoriasis is a chronic inflammatory skin disease with a prevalence of approximately 0.1-0.5% in Asians. It is characterized by widespread scaly erythematous macules that cause significant physical and psychological burdens for the affected individuals. The accelerated inflammation driven by the TNF-α/IL-23/IL-17A axis is now known to be the major mechanism in the development of psoriasis. Psoriasis is not a mere skin disease; it is significantly associated with cardiovascular diseases and metabolic syndrome, which suggests that the chronic skin inflammation extends the systemic inflammation beyond the skin. In this article, we review the epidemiological and pathological aspects of psoriasis and its comorbidities.

元の言語英語
ページ(範囲)1613-1619
ページ数7
ジャーナルInternal Medicine
56
発行部数13
DOI
出版物ステータス出版済み - 2017

All Science Journal Classification (ASJC) codes

  • Internal Medicine

フィンガープリント Cardiovascular and metabolic diseases comorbid with psoriasis: Beyond the skin' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用